Shingles Pain Treatment Will Benefit More Patients

�The medicated pain relief plaster,
(Versatis) is now approved by the Scottish Medicines Consortium (SMC) for
restricted use within NHS Scotland for patients suffering pain following
shingles(1) http://www.scottishmedicines.org.uk/smc/5850.hypertext markup language. This
reversal of the previous SMC decision (issued in February 2007) for
Versatis (5% lidocaine medicated plaster) is based on significant new
clinical and cost-effectiveness relative data and brings prescribing
availability of the treatment in bloodline with England and Wales. These new
data on Versatis testament be presented for the first time at the International
Association for the Study of Pain (IASP) Congress in Glasgow (17-22 August
2008).



The pain in the neck that persists for more than trinity months after the oncoming of
the shingles rash is called Post-herpetic Neuralgia (PHN) (2). PHN affects
approximately 200,000 people in the UK(3). PHN can be described as an
constant burning, stabbing or shooting pain. The pain can start several
weeks or even months after the shingles blizzard has bygone and potty continue for
weeks, months or old age(4).



Licensed in the UK in 2007, Versatis offers sustained pain relief
associated with PHN(5). Versatis is an innovative combination of local
analgesic lidocaine and a soft hydrogel plaster. Application of the plaster
to the tegument releases an appropriate grade of lidocaine into the skin to
impair the transfer of signals which would be associated with the
perception of hurting.



Based on clinical test data, Versatis is used as a continuous
once-daily 12 hours on/12 hours off applications programme schedule for 2-4 weeks and
provides rapid and continuous nuisance relief from 30 transactions after
application(6).



Dr Michael Serpell, Consultant and Senior Lecturer in Anaesthesia,
Glasgow says: "The newfangled recommendation from the SMC is to be welcomed. New
information supporting the role of Versatis in post-herpetic neuralgy will
farther establish that such a novel, non-systemic treatment approach shot offers
significant benefits in the old patient mathematical group who lose co-morbidities
and consequential polypharmacy".



Heather Wallace, Chairman of Pain Concern commented: "The SMC is to be
congratulated on its revised decision for Versatis. They've taken a huge
step forward in extending options for pain relief for people living with
neuropathic pain. This decision will alleviate a lot of suffering".



The risk of developing PHN increases with age - it is most vulgar in
people aged over 50. About half of shingles cases affecting hoi polloi of the
age of 65 will cause PHN(7,8).

Prescribing Information



Versatis 5% medicated plaster. Refer to the Summary of Product
Characteristics (SPC) for full inside information on side effects, warnings and
contra-indications before prescribing. Presentation: Versatis is a
medicated plaster (10cm x 14cm) containing 700 mg (5% w/w) of lidocaine in
an aqueous adhesive base. Indication: Treatment of neuropathic botheration
associated with previous herpes virus zoster infection (post-herpetic neuralgia,
PHN). Dosage and method of organisation: Adults and elderly patients: Use
up to three plasters for up to 12 hours, followed by at least a 12 hour
plaster-free interval. Cover painful area once casual. Apply the plaster to
intact, dry, non-irritated skin (after healing of the shingles). Remove
hairs in affected region with scissors (do not shave). Remove the beplaster
from sachet and its surface line drive before applying immediately to the skin.
Plasters may be cut to size. Patients under 18 years: Not recommended.
Contra-indications: Hypersensitivity to fighting substance, any excipients,
or local anaesthetics of amide type (e.g. bupivacaine, etidocaine,
mepivacaine and prilocaine). Warnings and precautions: Do not enforce to
inflamed or injured skin (e.g. active herpes zoster lesions, atopic
dermatitis or wounds), mucous membranes or the eyes. Plasters control
propylene ethylene glycol which english hawthorn cause skin irritation, methyl radical
parahydroxybenzoate and propyl parahydroxybenzoate which crataegus oxycantha cause allergic
reactions. Use with cautiousness in patients with severe cardiac impairment,
severe renal impairment or severe liverwort impairment. Interactions: No
clinically relevant interactions have been observed in clinical studies.
Absorption of lidocaine from the skin is low. Use with caution in patients
receiving Class I antiarrhythmic drugs (e.g. tocainide, mexitil) or
other local anaesthetics. Pregnancy and lactation: Do not use during
maternity or nursing. Undesirable effects: Very uncouth (greater than
or equal to 10%): administration website reactions (e.g. erythema, rash,
pruritus, burning). Uncommon (>0.1%-less than or equal to 1%): skin injury,
skin lesion. Very rare (less than or equal to 0.01%) but potentially
serious: anaphylaxis, hypersensitivity. Adverse reactions were
predominantly of mild and moderate loudness. Systemic adverse reactions
are unlikely. See SPC for full inside information. Overdose: Unlikely. If suspected,
remove plasters, provide supportive treatment (escort SPC). Legal
classification: POM. Marketing Authorisation number, pack sizes and basic
NHS cost: PL 21727/0016, 30 plasters (GBP 72.40). Marketing Authorisation
Holder: Grunenthal Ltd, Regus Lakeside House, 1 Furzeground Way, Stockley
Park East, Uxbridge, Middlesex, UB11 1BD, UK. Date of text: June 2008.
V0138

References:


1) Scottish Medicines Consortium, NHS Scotland, web site:
http://www.herpes.org.uk/shingles/index.hypertext mark-up language


2) Cunningham, A. and Dworkin, R. (2000) The Management of
post-herpetic neuralgia. BMJ 321, 778-779


3) Shingles Support Society. Bowsher D. Treatment of post-herpetic
neuralgia in the elderly. Available at:
http://www.herpes.org.uk/shingles/index.hypertext markup language


4) Herpes Viruses Association. Available at: http://www.herpes.org.uk


5) Versatis Summary of Product Characteristics


6) Baron R et al. Abstract presented at the Congress of the
European Federation of IASP Chapter, Istanbul 2006


7) Shingles Support Society. Bowsher D. Treatment of post-herpetic
neuralgia in the elderly. Available at:
hTTP://www.herpes.org.uk/shingles/index.html


8) http://cks.library.nhs.

Download Helios mp3

Artist: Helios: mp3 download    Genre(s):  Electronic Techno     Discography:      Ayres    Year: 2007    Tracks: 6      Eingya    Year: 2006    Tracks: 11      Unomia    Year: 2004    Tracks: 13 Boston-based ambient indie electronic creative person Helios is Keith Kenniff, a Berklee College of Music scholar wHO has likewise bypast under the cognomen Goldmund. As Helios, his recordings admit Unomia (2004), Eingya (2006), and in September 2007 a mini-album that for the first bag time featured Kenniff's delicate vocals. The prolific originative person likewise released deuce unofficial albums in 2005 via the Internet.

Tsunamis | Download mp3

�Mad Men�: Last Night�s Skirt Scene Was Don Draper�s Tony Soprano Moment

Remember how Tony Soprano took Meadow on that college trip, in the season-one episode "College"? And it was full of daddy-daughter bonding? Except for that whole

Lauer To Co-host Opening Ceremonies In Beijing

Raising his profile at the network considerably, NBC has named Matt Lauer, cohost of Today, to team up with Bob Costas to co-anchor the opening ceremonies of the Summer Olympics in Beijing on Aug. 8. The opening ceremonies of the 2006 Winter Olympics in Turin were co-anchored by Costas and Brian Williams. (Costas has co-anchored every Olympics possibility ceremonies since 1992.) The announcement came even as NBC Sports & Olympics Chairman was saying that the web is preparing for the possibility of major break news in Beijing during the Olympics. In an interview with the Hollywood Reporter, Ebersol said, "I always personally hope that it's fundamentally an Olympics about sports. But if it isn't going to be sports, we'll be ready for news."

Jamie Lynn Spears - Jamie Lynn Spears Gives Birth To Baby Daughter Maddie

Jamie Lynn Spears, the 17-year-old sister of Britney Spears, has given birth to her first child, Maddie Brian Aldridge, her representatives have confirmed.

The teenage actress delivered a baby girl at 09:33 local time (15:33 BST) on Thursday at a hospital near Liberty, Mississippi.

"Both mom and baby are healthy and happy," a rep for Jamie Lynn told OK! magazine.

"They are surrounded by their close relatives, including Jamie Lynn's older sister Britney, mother Lynne, father Jamie and brother Bryan."

Jamie Lynn told the magazine in December that she was three months into her pregnancy and was shocked when doctors confirmed the news.

She added that the father of the child was her boyfriend Casey Aldridge and that she had waited for two weeks before informing her family.

After news broke of Jamie Lynn's pregnancy, a publisher confirmed that a parenting book by her and Britney's mother was to be delayed indefinitely.

Lynne Spears was to publish Pop Culture Mom: A Real Story of Fame and Family in a Tabloid World on Mother's Day next year, but the book's release was shelved in the wake of Jamie Lynn's pregnancy announcement.

Jamie Lynn, a former star of Zoey 101, and Aldridge got engaged in March before purchasing a home in Liberty, where they plan on raising their new daughter.

Erin Sanders, who acted with Jamie Lynn on the Nickelodeon show, said the young mother's age would not be a barrier to her being a good mother.

"She is just a very good-hearted and warm person," he told People magazine.

"We would always hang out on the set and she is a lot of fun, so I think she's going to be an easygoing, fun mom."


20/06/2008 08:45:29

See Also

• Bow Wow - Bow Wow Fires Back At Loose-lipped Video Vixens
• R Kelly ‘Identified’ On Sex Tape
• Human Signals
• Live Review: Less Than Jake in Fort Lauderdale, FL

Mark Anthony

   
Artist: Mark Anthony

   Genre(s): 
Latin
   Other
   

---

Discography:


   
 Mended

   Year: 2002   
Tracks: 18


   
 Contra La Corriente

   Year: 2001   
Tracks: 15


   
 Desde Un Principio

   Year: 2000   
Tracks: 15

---

 





Funeral for music legend Bo Diddley being held in Gainesville, Fla.

Bluetech

   
Artist: Bluetech

   Genre(s): 
Ambient
   Electronic
   

---

Discography:


   
 Sines and Singularities

   Year: 2005   
Tracks: 11


   
 Prima Materia

   Year: 2004   
Tracks: 11


   
 Elementary Particles

   Year: 2004   
Tracks: 7

---

Evan Bartholomew, under the soubriquet Bluetech, produces his unique style of experimental noise from San Diego, CA. Classically trained on the piano for populace playacting, Bartholomew deviated from the traditional sounds and began to verbalize the rhythms that sprouted from inside him, and Bluetech was born. This resulted in his interpreting of nature's formulation of being, a sound that is dronal ambient, downtempo, improvisational. He devoured the electronic potentials for melodious look and conveyed it in IDM, digidub, and psychedelic trance.


Bartholomew created and runs his own art corporate in San Diego and does commercial reasoned design and output for both national and regional clients. He too writes and produces his own songs. "The Rubicon", "Prayers For Rain", and "Mezzamorphic" originally appeared on an EP released by Truffle Records, and brought the name Bluetech to a larger consultation. In September 2003, these songs appeared on Bluetech's number one album, Prima Materia, released by Waveform Records.





Nicole Richie's After Birth Party