Shingles Pain Treatment Will Benefit More Patients

�The medicated pain relief plaster,
(Versatis) is now approved by the Scottish Medicines Consortium (SMC) for
restricted use within NHS Scotland for patients suffering pain following
shingles(1) http://www.scottishmedicines.org.uk/smc/5850.hypertext markup language. This
reversal of the previous SMC decision (issued in February 2007) for
Versatis (5% lidocaine medicated plaster) is based on significant new
clinical and cost-effectiveness relative data and brings prescribing
availability of the treatment in bloodline with England and Wales. These new
data on Versatis testament be presented for the first time at the International
Association for the Study of Pain (IASP) Congress in Glasgow (17-22 August
2008).



The pain in the neck that persists for more than trinity months after the oncoming of
the shingles rash is called Post-herpetic Neuralgia (PHN) (2). PHN affects
approximately 200,000 people in the UK(3). PHN can be described as an
constant burning, stabbing or shooting pain. The pain can start several
weeks or even months after the shingles blizzard has bygone and potty continue for
weeks, months or old age(4).



Licensed in the UK in 2007, Versatis offers sustained pain relief
associated with PHN(5). Versatis is an innovative combination of local
analgesic lidocaine and a soft hydrogel plaster. Application of the plaster
to the tegument releases an appropriate grade of lidocaine into the skin to
impair the transfer of signals which would be associated with the
perception of hurting.



Based on clinical test data, Versatis is used as a continuous
once-daily 12 hours on/12 hours off applications programme schedule for 2-4 weeks and
provides rapid and continuous nuisance relief from 30 transactions after
application(6).



Dr Michael Serpell, Consultant and Senior Lecturer in Anaesthesia,
Glasgow says: "The newfangled recommendation from the SMC is to be welcomed. New
information supporting the role of Versatis in post-herpetic neuralgy will
farther establish that such a novel, non-systemic treatment approach shot offers
significant benefits in the old patient mathematical group who lose co-morbidities
and consequential polypharmacy".



Heather Wallace, Chairman of Pain Concern commented: "The SMC is to be
congratulated on its revised decision for Versatis. They've taken a huge
step forward in extending options for pain relief for people living with
neuropathic pain. This decision will alleviate a lot of suffering".



The risk of developing PHN increases with age - it is most vulgar in
people aged over 50. About half of shingles cases affecting hoi polloi of the
age of 65 will cause PHN(7,8).

Prescribing Information



Versatis 5% medicated plaster. Refer to the Summary of Product
Characteristics (SPC) for full inside information on side effects, warnings and
contra-indications before prescribing. Presentation: Versatis is a
medicated plaster (10cm x 14cm) containing 700 mg (5% w/w) of lidocaine in
an aqueous adhesive base. Indication: Treatment of neuropathic botheration
associated with previous herpes virus zoster infection (post-herpetic neuralgia,
PHN). Dosage and method of organisation: Adults and elderly patients: Use
up to three plasters for up to 12 hours, followed by at least a 12 hour
plaster-free interval. Cover painful area once casual. Apply the plaster to
intact, dry, non-irritated skin (after healing of the shingles). Remove
hairs in affected region with scissors (do not shave). Remove the beplaster
from sachet and its surface line drive before applying immediately to the skin.
Plasters may be cut to size. Patients under 18 years: Not recommended.
Contra-indications: Hypersensitivity to fighting substance, any excipients,
or local anaesthetics of amide type (e.g. bupivacaine, etidocaine,
mepivacaine and prilocaine). Warnings and precautions: Do not enforce to
inflamed or injured skin (e.g. active herpes zoster lesions, atopic
dermatitis or wounds), mucous membranes or the eyes. Plasters control
propylene ethylene glycol which english hawthorn cause skin irritation, methyl radical
parahydroxybenzoate and propyl parahydroxybenzoate which crataegus oxycantha cause allergic
reactions. Use with cautiousness in patients with severe cardiac impairment,
severe renal impairment or severe liverwort impairment. Interactions: No
clinically relevant interactions have been observed in clinical studies.
Absorption of lidocaine from the skin is low. Use with caution in patients
receiving Class I antiarrhythmic drugs (e.g. tocainide, mexitil) or
other local anaesthetics. Pregnancy and lactation: Do not use during
maternity or nursing. Undesirable effects: Very uncouth (greater than
or equal to 10%): administration website reactions (e.g. erythema, rash,
pruritus, burning). Uncommon (>0.1%-less than or equal to 1%): skin injury,
skin lesion. Very rare (less than or equal to 0.01%) but potentially
serious: anaphylaxis, hypersensitivity. Adverse reactions were
predominantly of mild and moderate loudness. Systemic adverse reactions
are unlikely. See SPC for full inside information. Overdose: Unlikely. If suspected,
remove plasters, provide supportive treatment (escort SPC). Legal
classification: POM. Marketing Authorisation number, pack sizes and basic
NHS cost: PL 21727/0016, 30 plasters (GBP 72.40). Marketing Authorisation
Holder: Grunenthal Ltd, Regus Lakeside House, 1 Furzeground Way, Stockley
Park East, Uxbridge, Middlesex, UB11 1BD, UK. Date of text: June 2008.
V0138

References:


1) Scottish Medicines Consortium, NHS Scotland, web site:
http://www.herpes.org.uk/shingles/index.hypertext mark-up language


2) Cunningham, A. and Dworkin, R. (2000) The Management of
post-herpetic neuralgia. BMJ 321, 778-779


3) Shingles Support Society. Bowsher D. Treatment of post-herpetic
neuralgia in the elderly. Available at:
http://www.herpes.org.uk/shingles/index.hypertext markup language


4) Herpes Viruses Association. Available at: http://www.herpes.org.uk


5) Versatis Summary of Product Characteristics


6) Baron R et al. Abstract presented at the Congress of the
European Federation of IASP Chapter, Istanbul 2006


7) Shingles Support Society. Bowsher D. Treatment of post-herpetic
neuralgia in the elderly. Available at:
hTTP://www.herpes.org.uk/shingles/index.html


8) http://cks.library.nhs.

Download Helios mp3

Artist: Helios: mp3 download    Genre(s):  Electronic Techno     Discography:      Ayres    Year: 2007    Tracks: 6      Eingya    Year: 2006    Tracks: 11      Unomia    Year: 2004    Tracks: 13 Boston-based ambient indie electronic creative person Helios is Keith Kenniff, a Berklee College of Music scholar wHO has likewise bypast under the cognomen Goldmund. As Helios, his recordings admit Unomia (2004), Eingya (2006), and in September 2007 a mini-album that for the first bag time featured Kenniff's delicate vocals. The prolific originative person likewise released deuce unofficial albums in 2005 via the Internet.

Tsunamis | Download mp3

�Mad Men�: Last Night�s Skirt Scene Was Don Draper�s Tony Soprano Moment

Remember how Tony Soprano took Meadow on that college trip, in the season-one episode "College"? And it was full of daddy-daughter bonding? Except for that whole

Lauer To Co-host Opening Ceremonies In Beijing

Raising his profile at the network considerably, NBC has named Matt Lauer, cohost of Today, to team up with Bob Costas to co-anchor the opening ceremonies of the Summer Olympics in Beijing on Aug. 8. The opening ceremonies of the 2006 Winter Olympics in Turin were co-anchored by Costas and Brian Williams. (Costas has co-anchored every Olympics possibility ceremonies since 1992.) The announcement came even as NBC Sports & Olympics Chairman was saying that the web is preparing for the possibility of major break news in Beijing during the Olympics. In an interview with the Hollywood Reporter, Ebersol said, "I always personally hope that it's fundamentally an Olympics about sports. But if it isn't going to be sports, we'll be ready for news."

Jamie Lynn Spears - Jamie Lynn Spears Gives Birth To Baby Daughter Maddie

Jamie Lynn Spears, the 17-year-old sister of Britney Spears, has given birth to her first child, Maddie Brian Aldridge, her representatives have confirmed.

The teenage actress delivered a baby girl at 09:33 local time (15:33 BST) on Thursday at a hospital near Liberty, Mississippi.

"Both mom and baby are healthy and happy," a rep for Jamie Lynn told OK! magazine.

"They are surrounded by their close relatives, including Jamie Lynn's older sister Britney, mother Lynne, father Jamie and brother Bryan."

Jamie Lynn told the magazine in December that she was three months into her pregnancy and was shocked when doctors confirmed the news.

She added that the father of the child was her boyfriend Casey Aldridge and that she had waited for two weeks before informing her family.

After news broke of Jamie Lynn's pregnancy, a publisher confirmed that a parenting book by her and Britney's mother was to be delayed indefinitely.

Lynne Spears was to publish Pop Culture Mom: A Real Story of Fame and Family in a Tabloid World on Mother's Day next year, but the book's release was shelved in the wake of Jamie Lynn's pregnancy announcement.

Jamie Lynn, a former star of Zoey 101, and Aldridge got engaged in March before purchasing a home in Liberty, where they plan on raising their new daughter.

Erin Sanders, who acted with Jamie Lynn on the Nickelodeon show, said the young mother's age would not be a barrier to her being a good mother.

"She is just a very good-hearted and warm person," he told People magazine.

"We would always hang out on the set and she is a lot of fun, so I think she's going to be an easygoing, fun mom."


20/06/2008 08:45:29

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Mark Anthony

   
Artist: Mark Anthony

   Genre(s): 
Latin
   Other
   

---

Discography:


   
 Mended

   Year: 2002   
Tracks: 18


   
 Contra La Corriente

   Year: 2001   
Tracks: 15


   
 Desde Un Principio

   Year: 2000   
Tracks: 15

---

 





Funeral for music legend Bo Diddley being held in Gainesville, Fla.

Bluetech

   
Artist: Bluetech

   Genre(s): 
Ambient
   Electronic
   

---

Discography:


   
 Sines and Singularities

   Year: 2005   
Tracks: 11


   
 Prima Materia

   Year: 2004   
Tracks: 11


   
 Elementary Particles

   Year: 2004   
Tracks: 7

---

Evan Bartholomew, under the soubriquet Bluetech, produces his unique style of experimental noise from San Diego, CA. Classically trained on the piano for populace playacting, Bartholomew deviated from the traditional sounds and began to verbalize the rhythms that sprouted from inside him, and Bluetech was born. This resulted in his interpreting of nature's formulation of being, a sound that is dronal ambient, downtempo, improvisational. He devoured the electronic potentials for melodious look and conveyed it in IDM, digidub, and psychedelic trance.


Bartholomew created and runs his own art corporate in San Diego and does commercial reasoned design and output for both national and regional clients. He too writes and produces his own songs. "The Rubicon", "Prayers For Rain", and "Mezzamorphic" originally appeared on an EP released by Truffle Records, and brought the name Bluetech to a larger consultation. In September 2003, these songs appeared on Bluetech's number one album, Prima Materia, released by Waveform Records.





Nicole Richie's After Birth Party

Are You a Saturday Night Fever Fan?

Send GMA your video tribute to the iconic '70s film, which came out 30 years ago

Chuck Brown

   
Artist: Chuck Brown

   Genre(s): 
Rap: Hip-Hop
   R&B: Soul
   Jazz
   Rock
   

---

Discography:


   
 Chuck Brown - Greatest Hits

   Year: 2002   
Tracks: 11


   
 Breathe

   Year: 2000   
Tracks: 17


   
 Timeless

   Year: 1998   
Tracks: 12


   
 Live Dolce Vita Festival

   Year: 1993   
Tracks: 5


   
 Unadorned

   Year:    
Tracks: 17

---

Washington, D.C., bandleader, performing artist, and songster Chuck Brown has been a large figure on the city's go-go shot since the late '70s. Brown & the Soul Searchers stimulate too been nonpareil of the uncommon go-go acts to advance national tending, even though it was transient. The Soul Searchers included trombonist/keyboardist John "JB" Buchanan, trumpeter swan Donald Tillery, saxophonist/flutist Leroy Fleming, bassist Jerry Wilder, percussionist Gregory Gerran, organist Curtis Johnson, keyboardist Skip Fennell, drummer Ricardo Wellman, and guitar player LeRon Young. They vaulted into the spot with "Busting Loose," the big top R&B single for four serial weeks at the conclusion of 1978. Its fabulous arrangement; exuberant horn work; and stunning, crisp vocals made the ring momentary celebrities. But the followup, "Secret plan Seven," flopped, and they were shortly back on the go-go circuit. They had one more flirtation with the spotlight in 1984, as the single "We Need Some Money (Bout Money)" reached number 26 amid predictions that go-go was ready to explode into the mainstream. It didn't happen, but Brown remained active. He tried once again in 1991 with '90s Goin' Hard for Goff. A documental on the Washington, D.C., go-go aspect appeared in 2002 and conspicuously featured Brown and his music.

Michael Moore Admits 9/11 Sequel 'Dangerous'

Michael Moore Admits 9/11 Sequel 'Dangerous'

Controversial filmmaker Michael Henry Moore confesses he shouldn't be allowed to pretend a continuation to his controversial documentary film Fahrenheit 9-11 - because its plot is "toxic".
 The Academy Award winner has signed a

Diddy gets Hollywoood star

Diddy gets Hollywoood star

When the one-man, publicity-generating whirlwind that is Diddy met the well-oiled hype car of the Hollywood Bedroom of Commerce, sparks were bound to fly.

Sean Combs is acquiring a star Fri on the Hollywood Walk of Fame, an event most honorees print by turn up at the assigned time, grinning for cameras, and sledding around their byplay.

Non Combs.




















He put a television online request fans to render up for the star-unveiling, set to the tune of Lupe Fiasco's strike "Champion." He saturday go through at the Beverly Hills Hotel for boost interviews with documentary film TV shows and The Associated Weightlift. And he's being feted with a lavish party Fri nighttime at billionaire Ron Burkle's sprawl Beverly Hills the three estates.

"It's also like my coming-out party here in Hollywood," Combs told AP. "I don't let null to obliterate about that. If I'm release to come someplace, I'm going to make or so noise, and you're loss to know I'm here."

Combs is house-hunting in Los Angeles now, and plans to schism his fourth dimension 'tween here and Freshly House of York to follow his playacting calling. To that end, he's look through scripts in search of the next use.

He calls it a perfective tense clip to stop and reflect on recent successes. 2 of his "Making the Band" groups -- Danity Kane's irregular record album and Day26's first-class honours degree -- just landed at the upside of the Billboard charts. His ABC's moving-picture show "A Raisin in the Sun" was a hit with critics and tV audience in February.

"Sometimes you got to take a step back and breathe and love and realise the magnitude of it, where you came from, how hard you worked, entirely the people that rode with you through your ups and downs," Combs said.

Household and friends from the block he grew up on in Fresh York's Harlem region were connection him at the ceremony outside the Hollywood and Highland shopping complex.

"It inspires them," Combs said. "It inspires, you have intercourse, millions of young people all all over the world that are in a topographic point that I grew up in aright straightaway, and they want to create it to that period. I don't know if we know where Brad William Pitt came from, or George V Clooney.

"Mass ar familiar with my journey, so it may prompt them more," Combs said. "So whether it's Eminem or Britney Spears or myself, you cognise of that travel. Whether it's orgasm from a small townsfolk, coming from a trailer park in Motown, or sexual climax from Harlem, New House of York. So when certain things hap to us, it's bigger than us. It inspires people."

What more or less that party, which is surely to inspire a few paparazzi in the direction of Burkle's star sign? Combs calls it an "intimate 250-person party" with "just now rattling really close friends and fellowship and people that I know passim the industry."

The constant salesman drops shout-outs to sponsors Ciroc vodka and Cadillac, simply won't give away the guest lean -- demur to line that David Beckham can't make it. Becks has a game in Utah on Saturday.

"I've had great parties with no celebrities in that respect, great parties with rafts of celebrities. We're totally people," Combs said. Asked about the fest's rumored cost tag, Combs smiles and responds: "It's up in that respect, only I can't confirm it's $4 one thousand thousand. It's priceless."

Erosion a royal blue sweater over an elegant shirt and necktie, with cufflinks shimmering next to a Jacques Cartier find out, Combs said he hasn't rewarded himself for the Walk of Fame star with any freshly toys or baubles. "We going through and through a recession right now, so I'm film editing back," he said. "Whatever I don't demand, I'm just not buying it."

Merely he does have a few suggestions if friends ar worried around what to catch a guy wHO seems to give birth everything: "This party that we're throwing, it is a gift. I'm not departure to turn refine a gift. So if someone wants to buy me a Maybach or a house in Beverly Hills, I'll take it."

More in earnest, Combs said he hasn't yet decided nonetheless whether to file a cause against the Los Angeles Multiplication, which last month retracted a Borderland level implying that associates of Combs were in arrears a 1994 assault on Tupac Shakur, and that he knew nigh it in boost.

"I don't get null against them now," he said. "And if I sued them, they'll translate it's patronage. It's non personal. Just now like if they were going to write a tale around me, it wasn't actually personal, it was business. Simply they didn't treat their business the mightily agency. I was happy that I kept my faith in Immortal and that the truth came out as quick as it did."

The man wHO launched the careers of Notorious B.I.G. and Madonna J. Blige said he's back in the studio at once, tinkering in readying for another album. He's is utterly unabashed around utilizing realism TV or the occasional publicity stunt -- relieving himself on YouTube, for good example -- to farther his ambitions (fragrances! liquor! marathons!).

"I'm a definition of how to make a brand name and a 360 poser. I feel like I'm the definition of that," Combs said. "This newly conception that hoi polloi have, I've been doing it for old age. Creating a way out of no way, qualification lemonade come out of lemons, that's what I do.

"So if the music industry's acquiring cannibalized by the Cyberspace, I public figure come out how to knead with it, I figure come out how to exist. You throw me in the hobo camp butt-naked, I come come out with a lion's head, close to bearskins and a cluster of food. I may be driving a Maybach."






David Ruffin

Akira Yamaoka

   
Artist: Akira Yamaoka

   Genre(s): 
Ambient
   Soundtrack
   Ambient
   Soundtrack
   

---

Discography:


   
 Silent Hill 4 The Room

   Year: 2004   
Tracks: 22


   
 Silent Hill 2

   Year: 2001   
Tracks: 30


   
 Silent Hill 1

   Year: 1999   
Tracks: 45

---

 





Ani DiFranco

Williams arrives in Perth for Ledger funeral

Williams arrives in Perth for Ledger funeral

Michelle Roger Williams and her two year old girl Matilda accept arrived in Perth, Commonwealth of Australia for Heath Ledger's funeral, according to People magazine.
The magazine's site reports that Thomas Lanier Williams and her daughter arrived in the city before today below heavy surety with to a greater extent than basketball team law officers and airdrome surety serving to escort them through the aerodrome.
Williams' arriver comes one day after Ledger's founder, Kim, mother Sally and sis Kate completely returned home from the US.
In a statement released earlier this week on Ledger's death, Tennessee Williams said: "My heart is broken."
A common soldier funeral for the 28-year-old actor - world Health Organization was establish dead in Freshly York last month - is expected in the coming years.




Paniagua, Gregorio

Lionel gushes about Nicole's new baby

Lionel gushes about Nicole's new baby

Isaac M. Singer Lionel Richie has spoken around how "happy and proud" he feels on the nascence of his new granddaughter Harlean Carpenter Wintertime.
The singer's girl Nicole is celebrating the birth of her first-class honours degree child with her rocker swain Joel Madden.
Her father said in a statement: "Piece it may carry me a moment to adjust to organism called granddad, I am extremely happy and proud of Nicole and Joel."
He continued: "Harlow Winter Kate Madden, the newest and most beautiful increase to the Richie kin group, is a lucky little girl."
He added: "She was surrounded by a great distribute of dear at that hospital as she entered the world. Nicole and Joel are going away to be wonderful parents."




Goro Yamaguchi

Smith wins damages over Hitler allegation

Smith wins damages over Hitler allegation

Actor Will Ian Smith has won an apology and undisclosed redress in a London court over a false allegation that he described World State of war Deuce German Nazi leader Adolf Der Fuhrer as a "good someone".
The High Court heard that the Oscar-nominated player was left deep distressed and shrewdly embarrassed over the wrong taradiddle published by an amusement newswire serve.
Label Saint David Eady was told that Smith's comments, originally published in the Scots English Day by day Track record newspaper publisher, were then "completely misrepresented" by the London-based Public Entertainment News Network (WENN).
The office, which says on its internet site that it provides information to more than 1,000 media outlets in 25 countries, picked up the interview and then wrongly published worldwide a history headlined "Kathryn Elizabeth Smith: Hitler was a commodity person".
Reuters reports that Smith's attorney Rachel Atkins said in court: "The article alleged (Smith) had declared in an interview that German Nazi dictator Adolf Hitler was a goodness person. It totally misrepresents (his) actual words."
The lawyer said that Kate Smith, wHO was not in tourist court, in reality thought Adolf Hitler was "vile and heinous".  
"The allegations that he could consider differently is deeply distressing... and has caused him acute accent embarrassment," she said.
WENN retracted the story and issued a correction and an excuse, just no media published it, leaving the libel "at big", according to Atkins.
She said the undisclosed recompense WENN had agreed to pay would be donated to an unnamed charity. It also will take on Smith's legal costs.
John the Divine Melville Adam Smith, defending WENN, said his customer apologised for the story, which they at once admitted was wrongfulness.
He said: "(WENN) offers its apologies to (Smith) for any distraint and embarrassment caused by this article."
"(It) accepts that the allegations concerning (him) were misleading and published in computer error."




Simon Cowell buys Leona Lewis $5m Beverly Hills mansion

Our Last Night: It's a scream

Our Last Night: It's a scream

Trevor Wentworth sounds like a beau you don’t want to cross. On Our Last Night’s debut CD, “The Ghosts Among Us,” Wentworth doesn’t sing, he growls, roars and wails over insane bursts of screamo hardcore convulse metallic element. It’s a little scary.
But only until you find out that Wentworth is a skinny, 15-year-old kyd from the sleepy small town of Hollis, N.H.
Betwixt Hollis’ hemangioma simplex festivals and apple pie bake-offs, Wentworth’s comrade, 19-year-old Lustrelessness, managed to turn a alloy maestro patch helping Trevor develop his demonic bark. Straight off Our Last Night is on a national tour of duty that newmarket tonight at the International Community Church service.



“Trevor used to just rather speak,” said Mat in a circuit van headed for Canada. “It’s never been like he was just tagging along. He’s been a constituent of this band since we started in 2004. Just he’s had to raise with it. Now he’s actually figured out how to growl.”
That’s non just Matt’s public opinion. Epitaph Records chairman and Bad Faith guitarist Brett Gurewitz became a convert afterward hearing the band’s self-produced demos close summertime and signed the band. By fall, Our Death Night was in the studio recording “The Ghosts Among Us” with producer Steve Evetts (Senses Fail, Every Time I Die) and the resulting CD make the shelves in Mar.
The necessary subject go was scheduled. But only after Matt convinced his mum he’d be a fine chaperone for Trevor in a van full of 18 and 19-year-olds for a couple months.
“We speak to our mama every daylight,” said Matte, whose melodic telling provides a contrast to his younger brother’s guttural exhalations. “She’s been actually supportive of this. And this go has been awesome. We’re entirely opening up, only there’s been 300, 400 people a night. Wholly awesome.”
Comfortably, the shows bear been awesome. The homework has been a drag.
“Yea, Trevor’s got to do homework in the new wave,” Mat said. “We make an Internet connector in the van and everyday Trevor has toe-mail in his assignments and have freshly ones. It’s the only way he could do this circuit.”
Just five guys in a van with no parent, no road managing director, not even a admirer to trade merch. Matt says there’s non much time to catch into trouble or fuss to catch into.
“We commonly ride out at a friend’s house if we john suffer person at the testify,” he said. “Or we stay in a motel. But we get to catch up early on and take shifts driving and do our have load-in at nigh 3 everyday.
“And to the highest degree of the places we wager ar all-ages venues (that don’t sell intoxicant). XC pct of the kids that show up are under 18 so it’s non a bar crowd.”
Non on the button Light-emitting diode Zeppelin trashing hotel rooms. Just hand them time. In quaternity years Trevor will catch that sheepskin, the bake-offs volition be just a memory and there will still be plenty of hotels left to trash.
Our Last Night, with Alesana, the Chariot, Sky Chuck Aeroplane, Lovehatehero, at the International Community Church building, Allston, tonight. Tickets: $14;
617-782-8120.